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The elastin peptide VGVAPG increases CD4(+) T-cell IL-4 production in patients with chronic obstructive pulmonary disease

BACKGROUND: In chronic obstructive pulmonary disease (COPD), lung-infiltrating inflammatory cells secrete proteases and participate in elastin breakdown and genesis of elastin-derived peptides (EP). In the present study, we hypothesized that the pattern of T lymphocytes cytokine expression may be mo...

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Detalles Bibliográficos
Autores principales: Lemaire, Flora, Audonnet, Sandra, Perotin, Jeanne-Marie, Gaudry, Pierre, Dury, Sandra, Ancel, Julien, Lebargy, François, Antonicelli, Frank, Deslée, Gaëtan, Le Naour, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7805078/
https://www.ncbi.nlm.nih.gov/pubmed/33435988
http://dx.doi.org/10.1186/s12931-020-01609-4