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Donor heart preservation with hypoxic-conditioned medium-derived from bone marrow mesenchymal stem cells improves cardiac function in a heart transplantation model

BACKGROUND: In heart transplantation, donor hearts inevitably suffer from ischemia/reperfusion (I/R) injury, which leads to primary graft dysfunction and affects patients’ survival rate. Bone marrow mesenchymal stem cells (BMSCs) have been reported to attenuate myocardial I/R injury via their paracr...

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Detalles Bibliográficos
Autores principales: Zhou, Pengyu, Liu, Hao, Liu, Ximao, Ling, Xiao, Xiao, Zezhou, Zhu, Peng, Zhu, Yufeng, Lu, Jun, Zheng, Shaoyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7805188/
https://www.ncbi.nlm.nih.gov/pubmed/33435991
http://dx.doi.org/10.1186/s13287-020-02114-7