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Targeting the RHOA pathway improves learning and memory in adult Kctd13 and 16p11.2 deletion mouse models

BACKGROUND: Gene copy number variants play an important role in the occurrence of neurodevelopmental disorders. Particularly, the deletion of the 16p11.2 locus is associated with autism spectrum disorder, intellectual disability, and several other features. Earlier studies highlighted the implicatio...

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Detalles Bibliográficos
Autores principales: Martin Lorenzo, Sandra, Nalesso, Valérie, Chevalier, Claire, Birling, Marie-Christine, Herault, Yann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7805198/
https://www.ncbi.nlm.nih.gov/pubmed/33436060
http://dx.doi.org/10.1186/s13229-020-00405-7