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Targeting the RHOA pathway improves learning and memory in adult Kctd13 and 16p11.2 deletion mouse models
BACKGROUND: Gene copy number variants play an important role in the occurrence of neurodevelopmental disorders. Particularly, the deletion of the 16p11.2 locus is associated with autism spectrum disorder, intellectual disability, and several other features. Earlier studies highlighted the implicatio...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7805198/ https://www.ncbi.nlm.nih.gov/pubmed/33436060 http://dx.doi.org/10.1186/s13229-020-00405-7 |