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Batch effects account for the main findings of an in utero human intestinal bacterial colonization study

A recent study by Rackaityte et al. reported evidence for a low level of bacterial colonization, specifically of Micrococcus luteus, in the intestine of second trimester human fetuses. We have re-analyzed their sequence data and identified a batch effect which violates the underlying assumptions of...

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Detalles Bibliográficos
Autores principales: de Goffau, Marcus C., Charnock-Jones, D. Stephen, Smith, Gordon C. S., Parkhill, Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7805227/
https://www.ncbi.nlm.nih.gov/pubmed/33436099
http://dx.doi.org/10.1186/s40168-020-00949-z