Cargando…

A temperature-sensitive Mycobacterium smegmatis glgE mutation leads to a loss of GlgE enzyme activity and thermostability and the accumulation of α-maltose-1-phosphate

BACKGROUND: The bacterial GlgE pathway is the third known route to glycogen and is the only one present in mycobacteria. It contributes to the virulence of Mycobacterium tuberculosis. The involvement of GlgE in glycogen biosynthesis was discovered twenty years ago when the phenotype of a temperature...

Descripción completa

Detalles Bibliográficos
Autores principales: Syson, Karl, Batey, Sibyl F.D., Schindler, Steffen, Kalscheuer, Rainer, Bornemann, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7805345/
https://www.ncbi.nlm.nih.gov/pubmed/33166604
http://dx.doi.org/10.1016/j.bbagen.2020.129783