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Reiterative infusions of MSCs improve pediatric osteogenesis imperfecta eliciting a pro‐osteogenic paracrine response: TERCELOI clinical trial

BACKGROUND: Osteogenesis imperfecta (OI) is a rare genetic disease characterized by bone fragility, with a wide range in the severity of clinical manifestations. The majority of cases are due to mutations in the COL1A1 or COL1A2 genes, which encode type I collagen. Mesenchymal stem cells (MSCs), as...

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Detalles Bibliográficos
Autores principales: Infante, Arantza, Gener, Blanca, Vázquez, Miguel, Olivares, Nerea, Arrieta, Arantza, Grau, Gema, Llano, Isabel, Madero, Luis, Bueno, Ana Maria, Sagastizabal, Belén, Gerovska, Daniela, Araúzo‐Bravo, Marcos J, Astigarraga, Itziar, Rodríguez, Clara I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7805402/
https://www.ncbi.nlm.nih.gov/pubmed/33463067
http://dx.doi.org/10.1002/ctm2.265