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COVID-19 virtual patient cohort reveals immune mechanisms driving disease outcomes

To understand the diversity of immune responses to SARS-CoV-2 and distinguish features that predispose individuals to severe COVID-19, we developed a mechanistic, within-host mathematical model and virtual patient cohort. Our results indicate that virtual patients with low production rates of infect...

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Detalles Bibliográficos
Autores principales: Jenner, Adrianne L., Aogo, Rosemary A., Alfonso, Sofia, Crowe, Vivienne, Smith, Amanda P., Morel, Penelope A., Davis, Courtney L., Smith, Amber M., Craig, Morgan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7805446/
https://www.ncbi.nlm.nih.gov/pubmed/33442689
http://dx.doi.org/10.1101/2021.01.05.425420