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Modelling preeclampsia: a comparative analysis of the common human trophoblast cell lines

Preeclampsia remains a challenge without an effective therapy. Evidence supports targetability of soluble fms‐like tyrosine kinase‐1 (sFlt‐1) and soluble endoglin (sEng), which are released excessively from the placenta under ischemic and hypoxic stresses. We compared four trophoblast cell lines, Be...

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Detalles Bibliográficos
Autores principales: Zhao, Jiawu, Chow, Rebecca P., McLeese, Rebecca H., Hookham, Michelle B., Lyons, Timothy J., Yu, Jeremy Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7805545/
https://www.ncbi.nlm.nih.gov/pubmed/33521587
http://dx.doi.org/10.1096/fba.2020-00057