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Recalibrating the epigenetic clock: implications for assessing biological age in the human cortex

Human DNA methylation data have been used to develop biomarkers of ageing, referred to as ‘epigenetic clocks’, which have been widely used to identify differences between chronological age and biological age in health and disease including neurodegeneration, dementia and other brain phenotypes. Exis...

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Detalles Bibliográficos
Autores principales: Shireby, Gemma L, Davies, Jonathan P, Francis, Paul T, Burrage, Joe, Walker, Emma M, Neilson, Grant W A, Dahir, Aisha, Thomas, Alan J, Love, Seth, Smith, Rebecca G, Lunnon, Katie, Kumari, Meena, Schalkwyk, Leonard C, Morgan, Kevin, Brookes, Keeley, Hannon, Eilis, Mill, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7805794/
https://www.ncbi.nlm.nih.gov/pubmed/33300551
http://dx.doi.org/10.1093/brain/awaa334