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Recalibrating the epigenetic clock: implications for assessing biological age in the human cortex
Human DNA methylation data have been used to develop biomarkers of ageing, referred to as ‘epigenetic clocks’, which have been widely used to identify differences between chronological age and biological age in health and disease including neurodegeneration, dementia and other brain phenotypes. Exis...
Autores principales: | Shireby, Gemma L, Davies, Jonathan P, Francis, Paul T, Burrage, Joe, Walker, Emma M, Neilson, Grant W A, Dahir, Aisha, Thomas, Alan J, Love, Seth, Smith, Rebecca G, Lunnon, Katie, Kumari, Meena, Schalkwyk, Leonard C, Morgan, Kevin, Brookes, Keeley, Hannon, Eilis, Mill, Jonathan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7805794/ https://www.ncbi.nlm.nih.gov/pubmed/33300551 http://dx.doi.org/10.1093/brain/awaa334 |
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