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O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease
The dopamine system in the midbrain is essential for volitional movement, action selection, and reward-related learning. Despite its versatile roles, it contains only a small set of neurons in the brainstem. These dopamine neurons are especially susceptible to Parkinson’s disease and prematurely deg...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7805798/ https://www.ncbi.nlm.nih.gov/pubmed/33300544 http://dx.doi.org/10.1093/brain/awaa320 |