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O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease
The dopamine system in the midbrain is essential for volitional movement, action selection, and reward-related learning. Despite its versatile roles, it contains only a small set of neurons in the brainstem. These dopamine neurons are especially susceptible to Parkinson’s disease and prematurely deg...
Autores principales: | Lee, Byeong Eun, Kim, Hye Yun, Kim, Hyun-Jin, Jeong, Hyeongsun, Kim, Byung-Gyu, Lee, Ha-Eun, Lee, Jieun, Kim, Han Byeol, Lee, Seung Eun, Yang, Yong Ryoul, Yi, Eugene C, Hanover, John A, Myung, Kyungjae, Suh, Pann-Ghill, Kwon, Taejoon, Kim, Jae-Ick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7805798/ https://www.ncbi.nlm.nih.gov/pubmed/33300544 http://dx.doi.org/10.1093/brain/awaa320 |
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