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EGR1 is a gatekeeper of inflammatory enhancers in human macrophages

Monocytes and monocyte-derived macrophages originate through a multistep differentiation process. First, hematopoietic stem cells generate lineage-restricted progenitors that eventually develop into peripheral, postmitotic monocytes. Second, blood-circulating monocytes undergo differentiation into m...

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Detalles Bibliográficos
Autores principales: Trizzino, Marco, Zucco, Avery, Deliard, Sandra, Wang, Fang, Barbieri, Elisa, Veglia, Filippo, Gabrilovich, Dmitry, Gardini, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806227/
https://www.ncbi.nlm.nih.gov/pubmed/33523892
http://dx.doi.org/10.1126/sciadv.aaz8836