Substrate-specific recognition of IKKs mediated by USP16 facilitates autoimmune inflammation

The classic NF-κB pathway plays crucial roles in various immune responses and inflammatory diseases. Its key kinase, IKKβ, participates in a variety of pathological and physiological processes by selectively recognizing its downstream substrates, including p105, p65, and IκBα, but the specific mecha...

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Detalles Bibliográficos
Autores principales: Yu, Jian-shuai, Huang, Tao, Zhang, Yu, Mao, Xin-tao, Huang, Ling-jie, Li, Yi-ning, Wu, Ting-ting, Zhong, Jiang-yan, Cao, Qian, Li, Yi-yuan, Jin, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806237/
https://www.ncbi.nlm.nih.gov/pubmed/33523871
http://dx.doi.org/10.1126/sciadv.abc4009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806237/
https://www.ncbi.nlm.nih.gov/pubmed/33523871
http://dx.doi.org/10.1126/sciadv.abc4009

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