Dysregulation of sonic hedgehog signaling causes hearing loss in ciliopathy mouse models

Defective primary cilia cause a range of diseases known as ciliopathies, including hearing loss. The etiology of hearing loss in ciliopathies, however, remains unclear. We analyzed cochleae from three ciliopathy mouse models exhibiting different ciliogenesis defects: Intraflagellar transport 88 (Ift...

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Detalles Bibliográficos
Autores principales: Moon, Kyeong-Hye, Ma, Ji-Hyun, Min, Hyehyun, Koo, Heiyeun, Kim, HongKyung, Ko, Hyuk Wan, Bok, Jinwoong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806262/
https://www.ncbi.nlm.nih.gov/pubmed/33382037
http://dx.doi.org/10.7554/eLife.56551

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806262/
https://www.ncbi.nlm.nih.gov/pubmed/33382037
http://dx.doi.org/10.7554/eLife.56551

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