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ATP and large signaling metabolites flux through caspase-activated Pannexin 1 channels

Pannexin 1 (Panx1) is a membrane channel implicated in numerous physiological and pathophysiological processes via its ability to support release of ATP and other cellular metabolites for local intercellular signaling. However, to date, there has been no direct demonstration of large molecule permea...

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Detalles Bibliográficos
Autores principales: Narahari, Adishesh K, Kreutzberger, Alex JB, Gaete, Pablo S, Chiu, Yu-Hsin, Leonhardt, Susan A, Medina, Christopher B, Jin, Xueyao, Oleniacz, Patrycja W, Kiessling, Volker, Barrett, Paula Q, Ravichandran, Kodi S, Yeager, Mark, Contreras, Jorge E, Tamm, Lukas K, Bayliss, Douglas A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806264/
https://www.ncbi.nlm.nih.gov/pubmed/33410749
http://dx.doi.org/10.7554/eLife.64787