Cargando…
ATP and large signaling metabolites flux through caspase-activated Pannexin 1 channels
Pannexin 1 (Panx1) is a membrane channel implicated in numerous physiological and pathophysiological processes via its ability to support release of ATP and other cellular metabolites for local intercellular signaling. However, to date, there has been no direct demonstration of large molecule permea...
Autores principales: | Narahari, Adishesh K, Kreutzberger, Alex JB, Gaete, Pablo S, Chiu, Yu-Hsin, Leonhardt, Susan A, Medina, Christopher B, Jin, Xueyao, Oleniacz, Patrycja W, Kiessling, Volker, Barrett, Paula Q, Ravichandran, Kodi S, Yeager, Mark, Contreras, Jorge E, Tamm, Lukas K, Bayliss, Douglas A |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806264/ https://www.ncbi.nlm.nih.gov/pubmed/33410749 http://dx.doi.org/10.7554/eLife.64787 |
Ejemplares similares
-
A quantized mechanism for activation of pannexin channels
por: Chiu, Yu-Hsin, et al.
Publicado: (2017) -
Deacetylation as a receptor-regulated direct activation switch for pannexin channels
por: Chiu, Yu-Hsin, et al.
Publicado: (2021) -
Structural mechanism of ATP-independent transcription initiation by RNA polymerase I
por: Han, Yan, et al.
Publicado: (2017) -
Unexpected link between an antibiotic, pannexin channels, and
apoptosis
por: Poon, Ivan K. H., et al.
Publicado: (2014) -
Cryo-EM structures of the autoinhibited E. coli ATP synthase in three rotational states
por: Sobti, Meghna, et al.
Publicado: (2016)