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Insulin Receptor Substrate p53 Ameliorates High-Glucose-Induced Activation of NF-κB and Impaired Mobility of HUVECs

Diabetes-related macrovascular and microvascular complications lead to poor prognosis. Insulin receptor substrate p53 (IRSp53) is known to act as a substrate for the insulin receptor tyrosine kinase, but its role in endothelial dysfunction remains unclear. Human umbilical vein endothelial cells (HUV...

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Detalles Bibliográficos
Autores principales: Liu, Fen, Chen, Yubin, Zhao, Shi, Li, Mei, Luo, Fanyan, Tang, Can-e
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806382/
https://www.ncbi.nlm.nih.gov/pubmed/33506012
http://dx.doi.org/10.1155/2021/3210586