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Activation of EP4 receptor limits transition of acute to chronic heart failure in lipoxygenase deficient mice

Aim: Immune responsive 12/15 lipoxygenase (12/15LOX)-orchestrate biosynthesis of essential inflammation-resolution mediators during acute inflammatory response in post-myocardial infarction (MI). Lack of 12/15LOX dampens proinflammatory mediator 12-(S)-hydroxyeicosatetraenoic acid (12-(S)-HETE), imp...

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Detalles Bibliográficos
Autores principales: Kain, Vasundhara, Ingle, Kevin A., Rajasekaran, Namakkal S., Halade, Ganesh V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806484/
https://www.ncbi.nlm.nih.gov/pubmed/33456570
http://dx.doi.org/10.7150/thno.51183