Smad3 deficiency promotes beta cell proliferation and function in db/db mice via restoring Pax6 expression

Rationale: Transforming Growth Factor-beta (TGF-β) /Smad3 signaling has been shown to play important roles in fibrotic and inflammatory diseases, but its role in beta cell function and type 2 diabetes is unknown. Methods: The role of Smad3 in beta cell function under type 2 diabetes condition was in...

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Detalles Bibliográficos
Autores principales: Sheng, Jingyi, Wang, Li, Tang, Patrick Ming-Kuen, Wang, Hong-Lian, Li, Jian-Chun, Xu, Bi-Hua, Xue, Vivian Weiwen, Tan, Rui-Zhi, Jin, Nana, Chan, Ting-Fung, Huang, Xiao-Ru, Ma, Ronald CW, Lan, Hui-Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806493/
https://www.ncbi.nlm.nih.gov/pubmed/33456576
http://dx.doi.org/10.7150/thno.51857

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806493/
https://www.ncbi.nlm.nih.gov/pubmed/33456576
http://dx.doi.org/10.7150/thno.51857

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