Exosome-based Ldlr gene therapy for familial hypercholesterolemia in a mouse model

Familial hypercholesterolemia (FH), with high LDL (low-density lipoprotein) cholesterol levels, is due to inherited mutations in genes, such as low-density lipoprotein receptor (LDLR). Development of therapeutic strategies for FH, which causes atherosclerosis and cardiovascular disease, is urgently...

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Detalles Bibliográficos
Autores principales: Li, Zhelong, Zhao, Ping, Zhang, Yajun, Wang, Jia, Wang, Chen, Liu, Yunnan, Yang, Guodong, Yuan, Lijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806494/
https://www.ncbi.nlm.nih.gov/pubmed/33456582
http://dx.doi.org/10.7150/thno.49874

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806494/
https://www.ncbi.nlm.nih.gov/pubmed/33456582
http://dx.doi.org/10.7150/thno.49874

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