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An optimized protocol for the generation of HBV viral antigen-specific T lymphocytes from pluripotent stem cells
In T cell-based cancer immunotherapy, tumor antigen (Ag)-specific CD8(+) cytotoxic T lymphocytes (CTLs) can specifically target tumor Ags on malignant cells. This promising approach drove us to adopt this strategy of T cell transfer (ACT)-based immunotherapy for chronic viral infections. Here, we de...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806515/ https://www.ncbi.nlm.nih.gov/pubmed/33490980 http://dx.doi.org/10.1016/j.xpro.2020.100264 |