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Protocol for pressure-clamped patch-clamp recording at the node of Ranvier of rat myelinated nerves

The patch-clamp recording technique is indispensable for studying ion channel functions of cells but is challenging to apply to the node of Ranvier, a key site where action potentials are conducted along myelinated nerves. We have developed a pressure-clamped patch-clamp recording method applying to...

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Detalles Bibliográficos
Autores principales: Kanda, Hirosato, Tonomura, Sotatsu, Dai, Yi, Gu, Jianguo G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806518/
https://www.ncbi.nlm.nih.gov/pubmed/33490982
http://dx.doi.org/10.1016/j.xpro.2020.100266