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Sialic acid-binding immunoglobulin-like lectin-15 expression on peritumoral macrophages is a favorable prognostic factor for primary central nervous system lymphoma patients

Sialic acid-binding immunoglobulin-like lectin-15 (Siglec-15) is a new immune checkpoint molecule and its role of primary central nervous system lymphoma (PCNSL) tumor microenvironment has been unclear. We explored the Siglec-15 and programed death-ligand 1 (PD-L1) expression in tumor tissues and an...

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Detalles Bibliográficos
Autores principales: Fudaba, Hirotaka, Momii, Yasutomo, Hirakawa, Taisei, Onishi, Kouhei, Asou, Daigo, Matsushita, Wataru, Kawasaki, Yukari, Sugita, Kenji, Fujiki, Minoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806611/
https://www.ncbi.nlm.nih.gov/pubmed/33441719
http://dx.doi.org/10.1038/s41598-020-79742-9