Cargando…

Maternal tadalafil therapy for fetal growth restriction prevents non-alcoholic fatty liver disease and adipocyte hypertrophy in the offspring

We aimed to investigate the effects of maternal tadalafil therapy on fetal programming of metabolic function in a mouse model of fetal growth restriction (FGR). Pregnant C57BL6 mice were divided into the control, L-NG-nitroarginine methyl ester (L-NAME), and tadalafil + L-NAME groups. Six weeks afte...

Descripción completa

Detalles Bibliográficos
Autores principales: Kawamura, Takuya, Tanaka, Hiroaki, Tachibana, Ryota, Yoshikawa, Kento, Maki, Shintaro, Toriyabe, Kuniaki, Takeuchi, Hiroki, Katsuragi, Shinji, Tanaka, Kayo, Ikeda, Tomoaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806616/
https://www.ncbi.nlm.nih.gov/pubmed/33441894
http://dx.doi.org/10.1038/s41598-020-80643-0