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Maternal tadalafil therapy for fetal growth restriction prevents non-alcoholic fatty liver disease and adipocyte hypertrophy in the offspring
We aimed to investigate the effects of maternal tadalafil therapy on fetal programming of metabolic function in a mouse model of fetal growth restriction (FGR). Pregnant C57BL6 mice were divided into the control, L-NG-nitroarginine methyl ester (L-NAME), and tadalafil + L-NAME groups. Six weeks afte...
Autores principales: | Kawamura, Takuya, Tanaka, Hiroaki, Tachibana, Ryota, Yoshikawa, Kento, Maki, Shintaro, Toriyabe, Kuniaki, Takeuchi, Hiroki, Katsuragi, Shinji, Tanaka, Kayo, Ikeda, Tomoaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806616/ https://www.ncbi.nlm.nih.gov/pubmed/33441894 http://dx.doi.org/10.1038/s41598-020-80643-0 |
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