Imprinting methylation predicts hippocampal volumes and hyperintensities and the change with age in later life

Epigenetic imprinting is important for neurogenesis and brain function. Hippocampal volumes and brain hyperintensities in late life have been associated with early life circumstances. Epigenetic imprinting may underpin these associations. Methylation was measured at 982 sites in 13 imprinted locatio...

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Detalles Bibliográficos
Autores principales: Lorgen-Ritchie, Marlene, Murray, Alison D., Staff, Roger, Ferguson-Smith, Anne C., Richards, Marcus, Horgan, Graham W., Phillips, Louise H., Hoad, Gwen, McNeil, Chris, Ribeiro, Antonio, Haggarty, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806645/
https://www.ncbi.nlm.nih.gov/pubmed/33441584
http://dx.doi.org/10.1038/s41598-020-78062-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806645/
https://www.ncbi.nlm.nih.gov/pubmed/33441584
http://dx.doi.org/10.1038/s41598-020-78062-2

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