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Divergent immune landscapes of primary and syngeneic Kras-driven mouse tumor models

Immune cells play critical functions in cancer, and mice with intact immune systems are vital to understanding tumor immunology. Both genetically engineered mouse models (GEMMs) and syngeneic cell transplant approaches use immunocompetent mice to define immune-dependent events in tumor development a...

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Detalles Bibliográficos
Autores principales: Gutierrez, Wade R., Scherer, Amanda, McGivney, Gavin R., Brockman, Qierra R., Knepper-Adrian, Vickie, Laverty, Emily A., Roughton, Grace A., Dodd, Rebecca D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806664/
https://www.ncbi.nlm.nih.gov/pubmed/33441747
http://dx.doi.org/10.1038/s41598-020-80216-1