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Small Extracellular Vesicles from adipose derived stromal cells significantly attenuate in vitro the NF-κB dependent inflammatory/catabolic environment of osteoarthritis

The therapeutic ability of Mesenchymal Stem/Stromal Cells to address osteoarthritis (OA) is mainly related to the secretion of biologically active factors, which can be found within their secreted Extracellular Vesicles including small Extracellular Vesicles (sEV). Aim of this study was to investiga...

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Detalles Bibliográficos
Autores principales: Cavallo, Carola, Merli, Giulia, Borzì, Rosa Maria, Zini, Nicoletta, D’Adamo, Stefania, Guescini, Michele, Grigolo, Brunella, Di Martino, Alessandro, Santi, Spartaco, Filardo, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806716/
https://www.ncbi.nlm.nih.gov/pubmed/33441764
http://dx.doi.org/10.1038/s41598-020-80032-7