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Prognostic value of blood-based fibrosis biomarkers in patients with metastatic colorectal cancer receiving chemotherapy and bevacizumab

A desmoplastic colorectal cancer stroma, characterized by excess turnover of the cancer-associated fibroblast derived collagens type III and VI, can lead to reduced drug-uptake and poor treatment response. We investigated the association between biomarkers of collagen type III and VI and overall sur...

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Detalles Bibliográficos
Autores principales: Nissen, Neel I., Kehlet, Stephanie, Boisen, Mogens K., Liljefors, Maria, Jensen, Christina, Johansen, Astrid Z., Johansen, Julia S., Erler, Janine T., Karsdal, Morten, Mortensen, Joachim H., Høye, Anette, Willumsen, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806753/
https://www.ncbi.nlm.nih.gov/pubmed/33441622
http://dx.doi.org/10.1038/s41598-020-79608-0