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Culture surface protein coatings affect the barrier properties and calcium signalling of hESC-RPE

Human pluripotent stem cell-derived retinal pigment epithelium (RPE) transplantation is currently under evaluation as treatment for macular degeneration. For therapeutic applications, cryostorage during cell production is typically needed with potential consequences to cell functionality. We have pr...

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Detalles Bibliográficos
Autores principales: Viheriälä, Taina, Sorvari, Juhana, Ihalainen, Teemu O., Mörö, Anni, Grönroos, Pyry, Schlie-Wolter, Sabrina, Chichkov, Boris, Skottman, Heli, Nymark, Soile, Ilmarinen, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806758/
https://www.ncbi.nlm.nih.gov/pubmed/33441679
http://dx.doi.org/10.1038/s41598-020-79638-8