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Altered hippocampal gene expression, glial cell population, and neuronal excitability in aminopeptidase P1 deficiency

Inborn errors of metabolism are often associated with neurodevelopmental disorders and brain injury. A deficiency of aminopeptidase P1, a proline-specific endopeptidase encoded by the Xpnpep1 gene, causes neurological complications in both humans and mice. In addition, aminopeptidase P1-deficient mi...

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Detalles Bibliográficos
Autores principales: Yoon, Sang Ho, Bae, Young-Soo, Oh, Sung Pyo, Song, Woo Seok, Chang, Hanna, Kim, Myoung-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806765/
https://www.ncbi.nlm.nih.gov/pubmed/33441619
http://dx.doi.org/10.1038/s41598-020-79656-6