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Altered hippocampal gene expression, glial cell population, and neuronal excitability in aminopeptidase P1 deficiency
Inborn errors of metabolism are often associated with neurodevelopmental disorders and brain injury. A deficiency of aminopeptidase P1, a proline-specific endopeptidase encoded by the Xpnpep1 gene, causes neurological complications in both humans and mice. In addition, aminopeptidase P1-deficient mi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806765/ https://www.ncbi.nlm.nih.gov/pubmed/33441619 http://dx.doi.org/10.1038/s41598-020-79656-6 |