Unraveling cardiolipin-induced conformational change of cytochrome c through H/D exchange mass spectrometry and quartz crystal microbalance

Cardiolipin (CL), a crucial component in inner mitochondrial membranes, interacts with cytochrome c (cyt c) to form a peroxidase complex for the catalysis of CL oxidation. Such interaction is pivotal to the mitochondrial regulation of apoptosis and is affected by the redox state of cyt c. In the pre...

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Detalles Bibliográficos
Autores principales: Sun, Sin-Cih, Huang, Hung-Wei, Lo, Yi-Ting, Chuang, Min-Chieh, Hsu, Yuan-Hao Howard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806790/
https://www.ncbi.nlm.nih.gov/pubmed/33441668
http://dx.doi.org/10.1038/s41598-020-79905-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806790/
https://www.ncbi.nlm.nih.gov/pubmed/33441668
http://dx.doi.org/10.1038/s41598-020-79905-8

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