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Sex-specific differences in peripheral blood leukocyte transcriptional response to LPS are enriched for HLA region and X chromosome genes

Sex-specific differences in prevalence are well documented for many common, complex diseases, especially for immune-mediated diseases, yet the precise mechanisms through which factors associated with biological sex exert their effects throughout life are not well understood. We interrogated sex-spec...

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Detalles Bibliográficos
Autores principales: Stein, Michelle M., Conery, Mitch, Magnaye, Kevin M., Clay, Selene M., Billstrand, Christine, Nicolae, Raluca, Naughton, Katherine, Ober, Carole, Thompson, Emma E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806814/
https://www.ncbi.nlm.nih.gov/pubmed/33441806
http://dx.doi.org/10.1038/s41598-020-80145-z