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Nrf2 regulates cell motility through RhoA–ROCK1 signalling in non-small-cell lung cancer cells

Nuclear factor-erythroid 2-related factor 2 (Nrf2) is a key transcriptional regulator of several antioxidant and anti-inflammatory enzymes. It binds to its endogenous inhibitor Kelch-like ECH-associated protein 1 (Keap1) in the cytoplasm under normal conditions. Various endogenous or environmental o...

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Detalles Bibliográficos
Autores principales: Ko, Eunsun, Kim, Dasom, Min, Dong Wha, Kwon, Seung-Hae, Lee, Ji-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806835/
https://www.ncbi.nlm.nih.gov/pubmed/33441941
http://dx.doi.org/10.1038/s41598-021-81021-0