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Propofol infusions using a human target controlled infusion (TCI) pump in chimpanzees (Pan troglodytes)

Chimpanzees are genetically and physiologically similar to humans. Several pharmacokinetic models of propofol are available and target controlled infusion (TCI) of propofol is established in humans, but not in chimpanzees. The purpose of this study was to investigate if human pharmacokinetic models...

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Detalles Bibliográficos
Autores principales: Miyabe-Nishiwaki, T., Kaneko, A., Yamanaka, A., Maeda, N., Suzuki, J., Tomonaga, M., Matsuzawa, T., Muta, K., Nishimura, R., Yajima, I., Eleveld, D. J., Absalom, A. R., Masui, K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806914/
https://www.ncbi.nlm.nih.gov/pubmed/33441704
http://dx.doi.org/10.1038/s41598-020-79914-7