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Propofol infusions using a human target controlled infusion (TCI) pump in chimpanzees (Pan troglodytes)
Chimpanzees are genetically and physiologically similar to humans. Several pharmacokinetic models of propofol are available and target controlled infusion (TCI) of propofol is established in humans, but not in chimpanzees. The purpose of this study was to investigate if human pharmacokinetic models...
Autores principales: | Miyabe-Nishiwaki, T., Kaneko, A., Yamanaka, A., Maeda, N., Suzuki, J., Tomonaga, M., Matsuzawa, T., Muta, K., Nishimura, R., Yajima, I., Eleveld, D. J., Absalom, A. R., Masui, K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806914/ https://www.ncbi.nlm.nih.gov/pubmed/33441704 http://dx.doi.org/10.1038/s41598-020-79914-7 |
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