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Fenofibrate attenuates doxorubicin-induced cardiac dysfunction in mice via activating the eNOS/EPC pathway

Endothelial progenitor cells (EPCs) improve endothelial impairment, which in turn restores endothelial function in patients with heart failure (HF). In the present study, we tested whether fenofibrate, with its anti-inflammatory and vasoprotective effects, could improve myocardial function by activa...

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Detalles Bibliográficos
Autores principales: Huang, Wen-Pin, Yin, Wei-Hsian, Chen, Jia-Shiong, Huang, Po-Hsun, Chen, Jaw-Wen, Lin, Shing-Jong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806979/
https://www.ncbi.nlm.nih.gov/pubmed/33441969
http://dx.doi.org/10.1038/s41598-021-80984-4