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Human leukocyte antigen class II quantification by targeted mass spectrometry in dendritic-like cell lines and monocyte-derived dendritic cells

The major histocompatibility complex II (HLA-II) facilitates the presentation of antigen-derived peptides to CD4+ T-cells. Antigen presentation is not only affected by peptide processing and intracellular trafficking, but also by mechanisms that govern HLA-II abundance such as gene expression, biosy...

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Detalles Bibliográficos
Autores principales: Casasola-LaMacchia, A., Ritorto, M. S., Seward, R. J., Ahyi-Amendah, N., Ciarla, A., Hickling, T. P., Neubert, H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807004/
https://www.ncbi.nlm.nih.gov/pubmed/33441579
http://dx.doi.org/10.1038/s41598-020-77024-y