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A chemokine-fusion vaccine targeting immature dendritic cells elicits elevated antibody responses to malaria sporozoites in infant macaques

Infants and young children are the groups at greatest risk for severe disease resulting from Plasmodium falciparum infection. We previously demonstrated in mice that a protein vaccine composed of the chemokine macrophage inflammatory protein 3α genetically fused to the minimally truncated circumspor...

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Detalles Bibliográficos
Autores principales: Luo, Kun, Gordy, James T., Zavala, Fidel, Markham, Richard B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807052/
https://www.ncbi.nlm.nih.gov/pubmed/33441615
http://dx.doi.org/10.1038/s41598-020-79427-3