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Early β adrenoceptor dependent time window for fear memory persistence in APPswe/PS1dE9 mice
In this study we demonstrate that 2 month old APPswe/PS1dE9 mice, a transgenic model of Alzheimer’s disease, exhibited intact short-term memory in Pavlovian hippocampal—dependent contextual fear learning task. However, their long-term memory was impaired. Intra-CA1 infusion of isoproterenol hydrochl...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807071/ https://www.ncbi.nlm.nih.gov/pubmed/33441593 http://dx.doi.org/10.1038/s41598-020-79487-5 |