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A role for orphan nuclear receptor liver receptor homolog-1 (LRH-1, NR5A2) in primordial follicle activation

Liver receptor homolog-1 (NR5A2) is expressed specifically in granulosa cells of developing ovarian follicles where it regulates the late stages of follicle development and ovulation. To establish its effects earlier in the trajectory of follicular development, NR5A2 was depleted from granulosa cell...

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Detalles Bibliográficos
Autores principales: Meinsohn, Marie-Charlotte, Hughes, Camilla H. K., Estienne, Anthony, Saatcioglu, Hatice D., Pépin, David, Duggavathi, Raj, Murphy, Bruce D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807074/
https://www.ncbi.nlm.nih.gov/pubmed/33441767
http://dx.doi.org/10.1038/s41598-020-80178-4