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A role for orphan nuclear receptor liver receptor homolog-1 (LRH-1, NR5A2) in primordial follicle activation
Liver receptor homolog-1 (NR5A2) is expressed specifically in granulosa cells of developing ovarian follicles where it regulates the late stages of follicle development and ovulation. To establish its effects earlier in the trajectory of follicular development, NR5A2 was depleted from granulosa cell...
Autores principales: | Meinsohn, Marie-Charlotte, Hughes, Camilla H. K., Estienne, Anthony, Saatcioglu, Hatice D., Pépin, David, Duggavathi, Raj, Murphy, Bruce D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807074/ https://www.ncbi.nlm.nih.gov/pubmed/33441767 http://dx.doi.org/10.1038/s41598-020-80178-4 |
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