Hydroxychloroquine can impair tumor response to anti-PD1 in subcutaneous mouse models

Hydroxychloroquine (HCQ) is a well-known anti-inflammatory drug but is also known as an anti-inflammatory drug. Here, we evaluate the influence of HCQ treatment on the effect of anti-PD1 tumor immunotherapy. Anti-PD1 therapy-sensitive tumor lines MC38, CT26, and RIL-175 were used to investigate the...

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Detalles Bibliográficos
Autores principales: Wabitsch, Simon, McVey, John C., Ma, Chi, Ruf, Benjamin, Kamenyeva, Olena, McCallen, Justin D., Diggs, Laurence P., Heinrich, Bernd, Greten, Tim F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807148/
https://www.ncbi.nlm.nih.gov/pubmed/33490900
http://dx.doi.org/10.1016/j.isci.2020.101990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807148/
https://www.ncbi.nlm.nih.gov/pubmed/33490900
http://dx.doi.org/10.1016/j.isci.2020.101990

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