Effect of Bimagrumab vs Placebo on Body Fat Mass Among Adults With Type 2 Diabetes and Obesity: A Phase 2 Randomized Clinical Trial

IMPORTANCE: Antibody blockade of activin type II receptor (ActRII) signaling stimulates skeletal muscle growth. Previous clinical studies suggest that ActRII inhibition with the monoclonal antibody bimagrumab also promotes excess adipose tissue loss and improves insulin resistance. OBJECTIVE: To eva...

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Detalles Bibliográficos
Autores principales: Heymsfield, Steven B., Coleman, Laura A., Miller, Ram, Rooks, Daniel S., Laurent, Didier, Petricoul, Olivier, Praestgaard, Jens, Swan, Therese, Wade, Thomas, Perry, Robert G., Goodpaster, Bret H., Roubenoff, Ronenn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2021
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807292/
https://www.ncbi.nlm.nih.gov/pubmed/33439265
http://dx.doi.org/10.1001/jamanetworkopen.2020.33457

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807292/
https://www.ncbi.nlm.nih.gov/pubmed/33439265
http://dx.doi.org/10.1001/jamanetworkopen.2020.33457

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