STOML2 potentiates metastasis of hepatocellular carcinoma by promoting PINK1-mediated mitophagy and regulates sensitivity to lenvatinib

BACKGROUND: Dysregulation of both mitochondrial biogenesis and mitophagy is critical to sustain oncogenic signaling pathways. However, the mechanism of mitophagy in promoting hepatocellular carcinoma (HCC) progression remains poorly understood. In this study, we investigated the clinical significanc...

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Detalles Bibliográficos
Autores principales: Zheng, Yahui, Huang, Chong, Lu, Lu, Yu, Kangkang, Zhao, Jing, Chen, Mingquan, Liu, Lu, Sun, Qingfeng, Lin, Zhifei, Zheng, Jianming, Chen, Jinhong, Zhang, Jubo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807703/
https://www.ncbi.nlm.nih.gov/pubmed/33446239
http://dx.doi.org/10.1186/s13045-020-01029-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807703/
https://www.ncbi.nlm.nih.gov/pubmed/33446239
http://dx.doi.org/10.1186/s13045-020-01029-3

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