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STOML2 potentiates metastasis of hepatocellular carcinoma by promoting PINK1-mediated mitophagy and regulates sensitivity to lenvatinib
BACKGROUND: Dysregulation of both mitochondrial biogenesis and mitophagy is critical to sustain oncogenic signaling pathways. However, the mechanism of mitophagy in promoting hepatocellular carcinoma (HCC) progression remains poorly understood. In this study, we investigated the clinical significanc...
Autores principales: | Zheng, Yahui, Huang, Chong, Lu, Lu, Yu, Kangkang, Zhao, Jing, Chen, Mingquan, Liu, Lu, Sun, Qingfeng, Lin, Zhifei, Zheng, Jianming, Chen, Jinhong, Zhang, Jubo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807703/ https://www.ncbi.nlm.nih.gov/pubmed/33446239 http://dx.doi.org/10.1186/s13045-020-01029-3 |
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