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High-resolution analysis of cell-state transitions in yeast suggests widespread transcriptional tuning by alternative starts

BACKGROUND: The start and end sites of messenger RNAs (TSSs and TESs) are highly regulated, often in a cell-type-specific manner. Yet the contribution of transcript diversity in regulating gene expression remains largely elusive. We perform an integrative analysis of multiple highly synchronized cel...

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Detalles Bibliográficos
Autores principales: Chia, Minghao, Li, Cai, Marques, Sueli, Pelechano, Vicente, Luscombe, Nicholas M., van Werven, Folkert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807719/
https://www.ncbi.nlm.nih.gov/pubmed/33446241
http://dx.doi.org/10.1186/s13059-020-02245-3